{"id":27812,"date":"2026-04-14T08:33:00","date_gmt":"2026-04-14T06:33:00","guid":{"rendered":"https:\/\/www.carnisostenibili.it\/?p=27812"},"modified":"2026-04-14T11:51:50","modified_gmt":"2026-04-14T09:51:50","slug":"plant-based-diets-and-fracture-risk","status":"publish","type":"post","link":"https:\/\/www.carnisostenibili.it\/en\/plant-based-diets-and-fracture-risk\/","title":{"rendered":"Plant-Based Diets and Fracture Risk"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><em>Plant-based diets, while perceived as healthy, raise emerging concerns, including a possible increased risk of bone fractures.<\/em><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In recent years, <strong>plant-based diets<\/strong> (primarily vegetarian and vegan) have entered the public debate as <strong>synonymous with healthy eating<\/strong>. However, when we move beyond the prevailing narrative and look at individual clinical outcomes, <strong>critical areas emerge that cannot be ignored<\/strong>. One of these concerns is <strong>bone health<\/strong>, particularly the <strong>risk of fractures<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The reference point remains the landmark <strong>EPIC-Oxford study<\/strong>, published in 2020 in BMC Medicine by Tong et al. (&#8220;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33222682\/\" target=\"_blank\" rel=\"noreferrer noopener\"><em>Vegetarian and vegan diets and risks of total and site-specific fractures: results from the prospective EPIC-Oxford study<\/em><\/a>&#8220;). This is a prospective cohort of <strong>nearly 55,000 British adults followed for approximately 18 years<\/strong>. The results are clear: <strong>compared to meat eaters, vegetarians and pescetarians<\/strong> (those who exclude meat and poultry but consume fish) <strong>have a moderately increased risk of fractures, while vegans have more than double the risk of hip fractures<\/strong>. Vegans also have an increased risk of total fractures and fractures of some specific sites, such as the leg and vertebrae.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><br><strong><em>Vegan diets: even careful planning may not fully mitigate bone health risks<\/em><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This finding remains highly significant, even after adjusting for important factors such as BMI, calcium and protein intake. This point is crucial because it refutes a widespread simplistic explanation: &#8220;It&#8217;s not the vegan diet itself; it&#8217;s just that they eat poorly. &#8220;<strong>The fact that these subjects still show a higher risk of fracture after adjusting for these factors calls into question the assumption that plant-based diets are nutritionally equivalent to omnivorous models if &#8220;well-planned<\/strong>. &#8220;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Evidence indicates that the problem isn&#8217;t limited to individual deficiencies, but concerns the overall nutritional makeup of these diets<\/strong>, particularly vegan ones, and their <strong>long-term impact on bone health<\/strong>. In other words, the data suggest that the plant-based dietary pattern may have inherent limitations for maintaining skeletal integrity, and that other factors are at play, related to the overall dietary pattern rather than just individual nutrients.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><br><strong><em>Fracture and osteoporosis risk in vegetarians compared with omnivores<\/em><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In subsequent years, <strong>these findings have not been refuted<\/strong>. On the contrary, <strong>a new meta-analysis published in 2025 in Nutrition Reviews<\/strong> (Ballarin et <span style=\"box-sizing: border-box; margin: 0px; padding: 0px;\">al., &#8220;<a href=\"https:\/\/academic.oup.com\/nutritionreviews\/advance-article\/doi\/10.1093\/nutrit\/nuaf241\/8340610\" target=\"_blank\"><em>Vegetarian and Vegan Diets and the Risk of Hip Fracture in Adults: A Systematic Review and Meta-analysis<\/em><\/a>&#8220;)\u00a0<strong>t<\/strong><\/span><strong>hat combined four large cohort studies totalling over 500,000 participants<\/strong> confirmed these findings. <strong>Vegetarians show an increased risk of hip fracture of approximately 25%, while vegans have an increase of approximately 75% compared to omnivores<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>This evidence was further confirmed by another very recent, large-scale meta-analysis published in 2025 in Clinical Nutrition<\/strong> (Zheng et al., &#8220;<a href=\"https:\/\/www.clinicalnutritionjournal.com\/article\/S0261-5614(25)00151-7\/fulltext#:~:text=To%20clarify%20these%20issues%2C%20we,diet%20modify%20the%20overall%20associations.\" target=\"_blank\" rel=\"noreferrer noopener\"><em>Plant-based diet and risk of osteoporosis: A systematic review and meta-analysis<\/em><\/a>&#8220;). The review included <strong>20 studies with over 243,000 participants<\/strong>, comparing <strong>vegetarians and vegans<\/strong> with omnivorous dieters. The results show that <strong>plant-based diets are associated with a significantly increased risk of lumbar spine osteoporosis<\/strong>, with more pronounced signs in vegans and subjects who have followed such diets for more than 10 years.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This increased <strong>fracture risk<\/strong> has a biological basis. The meta-analysis published in Nutrition Reviews in 2019 (Iguacel I et al. &#8220;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30376075\/\" target=\"_blank\" rel=\"noreferrer noopener\"><em>Veganism, vegetarianism, bone mineral density, and fracture risk: a systematic review and meta-analysis<\/em><\/a>&#8220;) had already clearly shown that <strong>vegetarians and vegans have lower bone mineral density<\/strong>, especially in the lumbar spine and femoral neck. <strong>The differences become clinically relevant in the long term, especially with advancing age<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><em>Ignoring these findings is not compatible with an evidence-based medical approach.<\/em><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">From a nutritional standpoint, <strong>the explanations are far from speculative<\/strong>. Scientific reviews on bone mineral density, including an Italian review published in Frontiers in Endocrinology in 2022, show that <strong>in plant-based diets, particularly vegan ones, calcium intake tends to be lower<\/strong> if fortified foods are not systematically used. <strong>Vitamin D is often insufficient<\/strong>. Protein intake, especially in less-structured versions of the diet, may be inadequate to maintain bone mass. Added to this is a <strong>lower average BMI, which represents an independent risk factor for hip fractures<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Finally, <strong>deficiencies of vitamin B12, zinc, selenium and other nutrients involved in bone remodelling processes<\/strong> and often critical in exclusively plant-based diets should not be overlooked (see also, for this purpose, the systematic review published in Nutrients in 2021, &#8220;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35010904\/\" target=\"_blank\" rel=\"noreferrer noopener\"><em>Nutrient Intake and Status in Adults Consuming Plant-Based Diets Compared to Meat-Eaters: A Systematic Review<\/em><\/a>&#8220;).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Overall, <strong>all available evidence indicates that plant-based diets, especially vegan ones, are not neutral with respect to skeletal health<\/strong>. On the contrary, they are consistently associated with an <strong>increased risk of fractures, particularly hip fractures<\/strong>. This finding must be taken into account in clinical practice, especially in older individuals, postmenopausal women, and those with existing risk factors for osteoporosis.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Ignoring or downplaying these findings for ideological reasons is not compatible with an evidence-based medical approach<\/strong>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p> [&hellip;]<\/p>\n","protected":false},"author":21,"featured_media":27814,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[681],"tags":[6941,6940,6943,4482,6942],"class_list":["post-27812","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-nutrition","tag-bone-health","tag-fracture-risk","tag-osteoporosis-risk","tag-plant-based-diets","tag-vegan-diets"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.1.1 - aioseo.com -->\n\t<meta name=\"description\" content=\"Plant-based diets, while perceived as healthy, raise emerging concerns, including a possible increased risk of bone fractures.\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"Luca Avoledo\"\/>\n\t<link rel=\"canonical\" href=\"https:\/\/www.carnisostenibili.it\/en\/plant-based-diets-and-fracture-risk\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO (AIOSEO) 5.0.1.1\" \/>\n\t\t<meta property=\"og:locale\" content=\"en_US\" \/>\n\t\t<meta property=\"og:site_name\" content=\"Carni Sostenibili -\" \/>\n\t\t<meta property=\"og:type\" content=\"article\" \/>\n\t\t<meta property=\"og:title\" content=\"Plant-Based Diets and Fracture Risk - 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